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CRISmono™ DNMT3A

CRISmono™ DNMT3A

PRODUCT SPECIFICATION

Input DNA

gDNA ≥ 20 ng

Platform

Sanger sequencing

* ABI Genetic Analyzer recommended

Target size

Size : 226 bp / Gene : DNMT3A

Applications

SNV (p.R882X)

PERFORMANCE EVALUATION

KEY FEATURES

Diagnostic kit based on Sanger sequencing

DNMT3A gene mutation detection kit based on Sanger sequencing

CRISPR/Cas9 system

Genetic scissors cut wild-type DNA and amplify mutant DNA

High sensitivity

Genetic scissors enhance the detection limits of Sanger sequencing

Convenience of diagnosis

Available for periodic monitoring and cusomization

PROCESS

  • 01 gDNA prep
  • 02 In vitro Cleavage
  • 03 PCR Amplification
  • 04 Clean up
  • 05 Sanger Sequencing
  • 06 Data Analysis

Whole blood

gDNA prep

In vitro Cleavage

PCR Amplification

Clean up

Sanger Sequencing

Data Analysis