cfDNA ≥ 20 ng
Hybridization Capture method
Illumina NextSeq 500/550 or NovaSeq 6000/X
Size : 332.8 kb / Gene : 106
UDI-UMI Adapter
Indel, SNV, CNV
In-house DB
NGS-based Hybridization capture method
Providing evidence for drugs and disease for mutations
Liquid biopsy to diagnose genetic mutations in cfDNA in blood
Enhance the accuracy of sequencing data by distinguishing
and eliminating PCR redundancy error
Blood
cfDNA prep
Library prep
Pooling
Target Hyb & Capture
Post Capture PCR
Beads Clean up
NGS & Analysis