CRISPincette™ MultiCancer
CRISPincette™ MultiCancer
PRODUCT SPECIFICATION
Input DNA
cfDNA ≥ 10 ng * 2 SET
Target enrichment
Amplicon method
Platform
Illumina MiSeq or MiSeq DX
* MiSeq Reagent Micro kit v2 or kit v2
Target region
Including 23 target regions
associated with cancer-related genes
Variant types
Indel, SNV
Analysis solution
In-house DB
PERFORMANCE EVALUATION
KEY FEATURES
Diagnostic kit based on NGS
NGS diagnostic kit to detect major
cancer-related mutations
Convenience of diagnosis
Enhanced diagnostic convenience using
cfDNA in the blood
CRISPR/Cas9 system
Amplify mutant DNA after cutting
wild-type DNA
High sensitivity
Enhanced detection limits using gcCas9
Reasonable cost
Compared to conventional NGS
diagnostic kits, a larger number of samples
can be analyzed in a single run
All-in-one platform
Integrated systems from diagnosis
to analysis at once
PROCESS
- 01 cfDNA prep
- 02 Target Amplification
(1st PCR) - 03 In vitro
Cleavage - 04 Library Clean up
- 05 Index
(2nd PCR) - 06 Pooling
- 07 NGS & Analysis
Blood
cfDNA prep
Target Amplification (1st PCR)
In vitro Cleavage
Library Clean up Removes cut wild-type DNA
Index (2nd PCR)
NGS & Analysis